Laurence Klotz, M.D. is the past Chief of Urology at Sunnybrook Health Sciences Centre and Professor of Surgery at the University of Toronto. He holds the Sunnybrook Chair of Prostate Cancer Research, is the Chairman of the World Uro-Oncology Federation, and past president of the Urological Research Society and the Canadian Urological Association. Dr. Klotz was the Founding Editor-in-Chief of both the Canadian Journal of Urology and the Canadian Urology Association Journal, and is now Editor Emeritus of the CUAJ. He was the founder and is chairman of the Canadian Urology Research Consortium (CURC). He is a member of the American Association of Genitor Urinary Surgeons.
Dr. Klotz obtained his medical degree from the University of Toronto and completed his residency at the University of Toronto Gallie Program in Surgery. He was a fellow at Memorial Sloan Kettering Cancer Centre in New York in uro-oncology.
Dr. Klotz is a widely published uro-oncologist with over 450 publications and 6 books. His main research interest has been prostate cancer. He is the Associate Editor of the Journal of Urology, responsible for Prostate Cancer. He serves on the boards of many medical/scientific organizations and journals, including the SUO, Prostate Cancer Canada, the journals Prostate Cancer and Prostatic Diseases, Brazilian Journal of Urology, Italian Journal of Urology, and World Journal of Urology. He is an honorary member of the AUA and the Chinese Urological Association.
Dr. Klotz has led many research studies in prostate cancer, including basic research studies of the role of micronutrients and diet in prostate cancer prevention, translational research, and clinical studies in every facet of prostate cancer. He has maintained a basic research laboratory for 30 years. His work has led to several patents and a biotech company. His clinical research interests have been in the areas of active surveillance, image targeted therapy, and androgen deprivation therapy.
Dr. Klotz led the multidisciplinary team at Sunnybrook who were the first to implement and report on a novel approach for patients with low risk prostate cancer based on conservative management, with strategic intervention for the minority of patients who were diagnosed as higher risk over time. This became known as Active Surveillance, a term coined by Dr. Klotz and subsequently widely adopted. Dr. Klotz was instrumental in initiating the concept of active surveillance and promoting its acceptance by urological and radiation oncology communities worldwide. He has authored more than 100 papers on this topic and given hundreds of talks and visiting professorships throughout the world.
In 1990, Dr. Klotz became the founding Editor in Chief of the Canadian Journal of Urology, which was the official journal of the Canadian Urological Association between 1992 and 2004. He remained editor until 2004. In 2005 he became the founding editor of the new Canadian Urology Association Journal, which he led as editor in chief until 2010. He is the Editor Emeritus of the CUAJ.
In 2000, Dr. Klotz founded the Canadian Urology Research Consortium (CURC), a national non-profit clinical research organization. This group, which has 150 members from across Canada, has successfully carried out approximately 30 prospective randomized multi-centre clinical trials in Canada.
In 2002, Dr. Klotz founded the World Urologic Oncology Federation (WUOF), an umbrella group for societies of Urologic Oncology around the world. Under his continued leadership, the Federation has grown from 5 to 20 member societies. In 2013, he co-initiated the Global Bladder Cancer Prevention Initiative, a WUOF initiative to bring smoking cessation management into urologic practice around the world. In 2018 he was elected chairman of uCARE, the SIU international research office.
He was awarded the Queen’s Jubilee Medal for meritorious public service in 2013, the University of Toronto Department of Surgery Lister Prize and the Society of Urologic Oncology Medal in 2014. He received the Order of Canada, Canada’s highest civilian award, in 2015 and the Richard Williams Award from the AUA in 2016. He received the Dean’s Lifetime Achievement Award from the University of Toronto in 2017.
Dr. Klotz is married to Ursula, and has 2 children. His son Alex is a physicist at MIT, and daughter Betsy is a recreational therapist. He relaxes with sports and music, including tennis, hockey, skiing, and jazz piano. In 2012 he founded ‘The Void’, a Canadian all-Urology band which has played frequently at the AUA and CUA.